Oncotargets and Therapy for Cancer

Some of Oncotarget articles on cancer focuses on strategies of pro-oncogenic cell signaling devices to address issues of human malignancies. This focus on a particular cancer cell may have identified both gene and drug therapy methods that can be used in treatment and prevention. The medical journal focuses on providing comprehensive information about the translational strategy that fights oncolytic infections. Check Oncotarget at scimagojr.com

Pro-oncogenic signals are the pathway that generates cancer in humans. The development of mutant versions of HSV-1 is a significant milestone in Oncolytic microbes research. The Ras-Smart virus is known as “ Signal Smart 1”. SS1 mutant is a different model of Oncolytic microbes that is designed to attack Cancer Stem Cells (CSCs) on tissue in a particular way.

HSV-1 and SS1 viruses are designed to remove all cancer stem cells that may have tumors. The CSC is a class of cells that can repopulate tumors and support different varieties of cells which make up the histological structures of cancer. No other therapy can efficiently eliminate CSCs in the body. The use of Oncolytic microbes is the best cancer therapy to prevent repopulating tumors in humans.

Listen: https://itunes.apple.com/us/podcast/oncotarget/id1294363732?mt=2

Most of the tumor antigens are known to be “self –antigens” making anti-tumor immune reactions face some inherent problems. Anti-cancer T cells prevent the formation of protective anti-cancer immunity. CD4 T cell can be used by doctors to facilitate the creation of specific reaction of antigen CD8+ cytolytic T lymphocyte (CTL).

Other approaches that can be used to restrict CSCs cells from multiplying include, generation of immunogenic DC that make inhibitory molecules such as IL-10; HSV-VP22 and carrier protein for simultaneous production of CD8 T and CD4 T cell response; utilization of “self-translatable.” The formation of specific donor customized MHC class 1 controlled anti-tumor CD8+ CTL and CD4+ “multifunctional” T cells by creating human peripheral blood obtained from T cells with an MHC class 1 prevented transgenic T cell receptor( TCR), separated from melanoma patient-derived CD8 + CTL.

Onctotarget researchers have consistently sought to produce valuable information regarding cancer treatment and biological processes. Their continued hard work provides options for patients and paves the way to the future of oncology treatments. Learn more at Research Gate.

Getting the Most from Your Talkspace Experience

If your doctor has recommended that you go to therapy, you might be wondering how to begin making appointments and finding the time to get there. If you do not have health insurance, therapy can also be a true expense that seems next to impossible to afford. Unfortunately, forgoing your mental health and not seeing a therapist is not going to do you any good. It’s been found that people who suffer from depression do not take care of themselves in the way that they would if they were feeling mentally well. Other disorders, like bipolar, can affect your relationships and career.

If you’ve struggled with traditional therapy and find it to be both inconvenient and expensive, it’s time to take a different route. This route is in the form of Talkspace, which is a New York-based app designed to make getting therapy easier and more affordable. With Talkspace, you simply download an app and create an account that is specific to your needs. Once you’re matched with a therapist, you will be able to video chat with them, send messages or simply communicate them by text. Whatever is most comfortable for you at the moment, Talkspace makes available to you.

The beauty about using Talkspace as a therapy option is that it’s ideal for individuals who are simply too mentally unwell to leave their homes. People with agoraphobia or panic disorder may forgo leaving their house and avoid going to therapy because of this fear. If this has been an issue for you in the past, Talkspace closes this gap and brings your therapy into your home where you are most comfortable. There are thousands of people currently using Talkspace with great success, and it’s a viable alternative to the traditional therapy that you’ve been going to for years.

George Soros Contribution to Democracy and Human Rights

The founder of the Open Society Foundation, George Soros has been the critical donor for his organization. Besides supporting the formation, he has contributed to the support of several groups and individuals around the globe. Mr. Soros recent donation of $1.8 billion to his foundation was reported to be the highest private transfer to a single organization globally. His philanthropic support was to enable future functionality of the group.

Open Society Foundation has its services in 120 countries across the globe. It commits to enhance human rights and democracy. For the 30 years, it has been in operation, over $30 billion was donated by Mr. Soros to support its work. Among many programs implemented by the foundation, the rights of lesbians and gays are not left out. The Open Society Foundation makes sure that these individuals get protection from police abuse.

The impact of Open Society Foundation has extensively impacted the world due to the endless support by George. His leadership has seen support for other organizations and individuals. The group focuses operations on ensuring equality, upholding justice, government accountability and freedom of communication.

In 2004, Mr. Soros made sure the foundation supported Roma art and culture treatment centers during the Ebola epidemic. His organization also managed to pay school fees for less privileged and promising students. The entrepreneur was in the forefront to end the United States election crisis in 2016 during the hate incidents. He donated $10 million towards the peace-preaching to end violence experienced in the period, learn more about George Soros.

George Soros support for Democrats was also witnessed during the Clinton and Trump campaigns for the presidency. He gave millions to super PACs to the downfall of Mr. Trump. He even gambled the defeat of Trump through a bet worth $1 billion.

Several leaders in the civil society have partnered with the Open Society Foundation. Its programs are geared towards the benefits of humanity that are felt extensively and intensely in the world. Some of its associates are the Roma in the Eastern Europe and Africa Americans in Cleveland, and http://www.forbes.com/profile/george-soros/.


About George Soros

George Soros was born in 1930 in Budapest, Hungary. In 1947, he joined London School of Economics where he was able to study at the philosopher Karl Popper fleet. He attained degree in philosophy in 1951 and a masters of the same in 1954 from London School of Economics.

George Soros is among the world’s successful investors. Having worked in several jobs, Soros managed to grow his career. Before starting his entrepreneurship, he worked in England at Merchant bank. The investor launched his first hedge fund, known as Double Eagle in 1969. The returns from this first venture contributed to the establishment of Soros Fund Management in 1970. The Double Eagle later transformed to the Quantum Fund which doubled assets to $25 million by 2011.

Mr. Soros is a supporter of the American liberal and progressive sources. He uses his foundation, Open Society to distribute donations. The philanthropist donated over $11 billion between 1979 to 2011. His support to poverty reduction, transparency enhancement, and scholarships around the word recorded to $ 12 billion, and read full article.

Try The New, Flavorful Crystal Lip Balm From EOS

An essential item to carry in your purse is lip balm. Not only does it add luscious shine to your lips, it also helps keep them healthy and moisturized. Made with the vegan-friendly ingredients of avocado, shea butter, coconut, sunflower oils, and castor, Crystal Lip Balm from Eos lives up to the brand’s mission to create flavorful, health products. Costing an affordable $5, it is also waxless, and come in unique new packaging. You may buy it here on amazon.com. Eos is famous for its spherical container but has decided to step outside of the box this time. Available in sleek, pyramid packaging, Crystal Lip Balm by Eos is a must have. The clear-colored, hydrating lip balm is hypoallergenic and tastes wonderful. Scented Hibiscus Peach and Vanilla Orchid are the two flavors available when purchasing Eos Crystal Lip Balm.

Find more awesome related articles here on usmagazine.com.

Eos started with a desire to modernize the selections of lip balm. Brands such as Chapstick dominated the lip balm industry in the 20th century but did not evolve much or consider the preferences of its female loyalists. Women have made complaints of lack of flavor and the packaging being easily lost in purses. Eos decided to do something about it and is now a major contender against the long-established brands. Cofounded by Sanjiv Mehra, Craig Dubitsky, and Jonathan Teller; they wanted to give the public what they craved.

The trio used their own money for startup capital and created a feminine lip balm brand in a world of unisex lip balm offerings, read more here. The rounded, signature shape of the packaging was distinctive; Beauty bloggers praised Eos, and the celebrity endorsements followed. Britney Spears and Miley Cyrus used Eos in videos; Taylor Swift became an Asian ambassador. A social media fave, followers of the brand are loyal, vigilant, and celebrate the Eso brand by liking and sharing with their own followers.

See this great video, https://www.youtube.com/watch?v=2_UEa9u13Mc.


Jason Hope: The Intricacy IoT

The future is exciting and sometimes a little scary. There are new products and technologies sprouting up everywhere that you look. While some are intriguing, a lot of them come with a bit of a learning curve. Consumers don’t really understand the importance of the technology behind the products they are investing in, they simply want the next best thing. Businessman, futurist, and philanthropist Jason Hope can now add the title author to his long list of achievements with his new e-book detailing one of these technologies, the Internet-of-Things, or IoT. The new e-book, entitled “Understanding the Internet-of-Things Revolution: A Quick Guide for Thriving in the IoT Era”, is set to propel Hope to the top of a yet another new industry.

The e-book is Hope’s attempt to educate the public about the IoT network that feeds their electronic devices. He explains that IoT allows devices to communicate with one another and share information via the internet. They can do this quickly and effectively, while also interacting with their human users. This IoT network poses several new opportunities for the future of technology. As the technology grows, it will also become even more human-centric than it is now. Automation will become more widespread as technology becomes more remote. Hope foresees a huge growth in this technology sector and he wants to prepare his readers for that eventuality.

One should not discount the value associated with this new reading material from Jason Hope. The IoT is set to explode in the coming years with over 30 billion objects and a projected global market value of 7.1 trillion dollars. While it might be easy to think that you can catch up with the latest technology, Hope is trying to get his readers ahead of it, for once.

Hope is a valuable resource when it comes to all things tech. He is a graduate of the W.P. Carey School of Business with an MBA and a degree in Economics. He not only started his own tech company, but it has flourished under leadership. He is an active philanthropist and invests large amounts of money into his community. In addition to his business success, Hope has also established himself as a skilled futurist. He can make accurate predictions about the technology market, and he uses those predictions to advance his portfolio of companies. Clearly, Hope is an expert in his field and he is screaming that the future is IoT. Purchase his e-book today at Amazon.com.

Read More: entrepreneur.wiki/Jason_Hope

Professional, Glen Wakeman Lends Advice To Start-Up Businesses

There are many small business getting their foot in the door for the first time and could benefit greatly from professional advice. It is important for your start-up to be successful, generate cash flow,or a strong audience within a few weeks of starting. Your business will depend on sustainability in an unstable financial market and ones driven behind misinformation says, Glen Wakeman. As a former CEO, he understands the importance of knowing what it takes to compete in a competitive business industry. Wakeman has expertise in the economics and finances with a degree from the University of Chicago. View Glen Wakeman’s profile linkedin.com.

Glen Wakeman teaches his clients how to create a business plan which is the key to success. He helps you determine if, it’s something you would like to make a profession and how to extend your portfolio. More importantly, he teaches you how to start with your own money to avoid huge debt. Starting your business is a great way to start your business off debt free. He also admits it is important to take care of yourself against liabilities that will come by other corporations or consumers. Wakeman teaches you how to insure your business and remain operational in a competitive business network with many services and products.

Who Is Glen Wakeman

Highly successfully business professional, Glen Wakeman is first and far most a business professional. He is also an investor and financial mentor for many successful small businesses currently in existence. He is also a strong believer in giving back to the communities they serve. For example he donated $5,000 to the successful relief efforts of the recent victims of Hurricane Maria in Puerto Rico. He was one of the first to advice other businesses to follow in his footsteps and take the self initiative to give back to many ravished communities. He was able to raised over $24,000+ dollars in additional funding.

Visit: http://www.glenwakeman.com/

You’re invited to visit the exclusive Glen Wakeman LinkedIn account to learn more about his professional accomplishments and where to get business advice about your start-up. Glen Wakeman wants you to know you don’t have to start a new business on your own because his financial services advice is there to help. Bring your failing small business back with his financial advice as well as making a success out of your current business endeavors with advice from financial expert, Glen Wakeman. Follow Glen Wakeman’s profile on Twitter.

The Brown Modeling Agency is Helping to Make Stars

In 2015, Wilhelmina Austin acquired Heyman Talent-South and relaunched the brand as the Brown Modeling Agency. Since that time, this modeling agency has grown to become one of the largest in the Austin area, and the only to offer full-services to their clients. Under the leadership of Justin Brown this agency is now stronger than ever.


Aspiring models will find tremendous opportunity at the Brown Agency. This company’s goal is to provide their clients with as many options as possible with brands such as Louis Vuitton, Dell, Toyota, and thousands of others. It provides models with a fantastic way to reach companies that may otherwise have been unavailable.


Founder Justin Brown knows how to take care of his clients, as he was a model himself during his college years. He studied business management in college before going back to his modeling routs; this time as a mentor to young aspiring models. Today, the Brown Modeling Agency represents hundreds of models from around the country.


Many of the models at the Brown Agency have also been featured in major fashion shows around the world. Austin Fashion Week, New York Fashion Week, and many other shows have utilized the talent from this world-class agency. As Justin Brown puts it, “the days of runway shows in bars are over.”


Austin has become a modeling and fashion hot spot over the years. Models working here are known to have a more laid-back style than cities such as Los Angeles or New York. “In Austin, they are looking for a more cool vibe, more alternative — piercings, tattoos, funky hair,” Brown says. “Dallas, for instance, more conservative.” Check out blog.brownagency.co to see more.



Unlike some companies charging exorbitant rates to their models, the Brown Modeling Agency charges only 20 percent for modeling jobs, 15 percent for non-union commercial film or television gigs, and only 10 percent for union jobs.


For young aspiring models, the Brown Modeling Agency is one of the best companies to work for. They offer a tremendous amount of opportunities such as television spots and runway shows, and work diligently to ensure a bright future in the modeling industry. Check them out today to learn more about how to become part of their team.



Jorge Moll Helps Explain How Giving Is Beneficial To Your Health

As Christmas approaches, the holiday season is in full swing. Research has shown that there are many positive benefits to giving. Giving can help people live happier and healthier lives. Regardless of whether you are giving gifts, donating to a charity, or volunteering, here are a few ways that being selfless can have a positive impact on your life.

Better Overall Health

Giving to others has been shown to help people who are dealing with serious illnesses, such as HIV. Volunteering can help increase a person’s life expectancy. This is especially true for elderly people. Giving has been shown to reduce stress. A study conducted by Johns Hopkins University found that people who help others have a lower blood pressure than people who don’t. Follow Jorge Moll on Linkedin.

General Happiness

Research has shown that giving money to others can increase someone’s happiness more than them spending money on themselves. According to Jorge Moll and the National Institutes of Health, there is a link between people giving money to charity and their brain. People begin to experience more pleasure and have a general glow. Giving can also release endorphins in the brain.

Feeling Grateful

Jorge Moll says that research has shown that giving causes people to feel gratitude. Gratitude can create important social bonds. Being grateful can boost self esteem levels. Moll says that finding something to be grateful for everyday is one way that people can increase their overall happiness.

Setting Yourself Up For The Future

When people give, they are more likely to receive something in the future. Giving allows people to develop a sense of trust that strengthens bonds. Developing a positive attitude allows people to control their mental and physical health. Giving brings people closer together, and Moll believes that will lead to more interdependence within the community. Watch this video on youtube.com.

Influencing Others

The giving attitude can spread through a community. When someone watches another person being kind, it can inspire them, regardless of whether they know the person or not. Moll says that giving can release oxytocin, which creates of feelings of warmth. People will start to feel more empathy towards others.

Learn more: http://www.fehosul.org.br/fehosul/paulo-chapchap-e-jorge-moll-apresentam-visoes-inovadoras-da-gestao-empreendedora-em-saude/

Review of the New EOS, Vegan Flavors

EOS, or Evolution of Smooth, came into the lip balm market about seven years ago. When these lip balms hit the shelves of local drugstore and supermarkets, people could not get enough! Beauty and fashion magazines raved about the colorful packaging and tasty flavors. When celebrities were spotted on social media using them, the world went crazy for them!

According to usmagazine.com, the concept of the egg-shaped package was a way to get customers to use all five of their sense while using the lip balms. EOS also wanted to make a product that would be priced perfectly for any budget. When the lip balms were first released, they were priced at $3 in order to compete with others in the lip balm market.  Once EOS discovered just how popular they had become, they started to focus more on making a connection with their customers. Hurry and buy here at amazon.com!

Part of the connection that EOS has made is by using all-natural and organic ingredients, never testing on animals, and now releasing a completely vegan line of products. There are two vegan crystal flavors: Hibiscus Peach and vanilla Orchid. These products are made with jojoba oil and vitamin E. By avoiding the use of beeswax, EOS has now opened their market to vegans who could not buy their lip balms before.

After trying the new vegan flavors, the results are in! Both flavors of EOS lip balm make the lips feel incredibly soft and smooth without the use of petrolatum, read more. EOS will plan on making new vegan flavors, but so far these two have been a huge hit with their users.

Read this great review, http://www.allure.com/review/eos-lip-balm-sphere!

Get The Rich Glow Of EOS Lip Balm

How serious is beauty to you? Do you want all-natural products and most retailers push the traditional brands with all the hard to read ingredients? The EOS brand gives their customers the opportunity to indulge in a unique brand with essential oil and vitamins says usmagazine.com. You can give the soft skin on your lips therapy with completely organic ingredients. Hydrate your skin with one of the too brands in the industry for under $5, purchase here on amazon.com. That’s right; EOS products are priced for all budgets, but you may have seen your favorite celebrity wearing it or pulling it from their designer bag or camera.

Their containers are cute and designed to be easy to find at the bottom of your cluttered purse. Believe it or not, they design their lip balm containers with their customers in mind, click here. For example, their new Crystal line comes in a see through container which is a must have when you’re looking for protection and cute. Don’t miss a great opportunity to find other organic products from their grandfather brand Evolution of Smooth. You can find descriptive products like body butter, lotion, and shaving cream. Join the exclusive EOS lip balm family and find the unique flavor and scent to help accent and protect your lips.

View this helpful link, http://www.allure.com/review/eos-lip-balm-sphere.